Opioid addiction is a severe public health crisis. Medication-assisted treatments (MAT) play a crucial role in helping people recover from this addiction.
As per the CDC, provisional data from 2022 shows that over 82,000 people lost their lives to opioid overdose in 2022. The number of drug overdose deaths using synthetic opioids has been rising in comparison to 2021. Methamphetamine and other psychostimulants with potential for misuse also showed an increasing trend in overdose deaths.
Nevertheless, these medications come with their own set of challenges. They can produce side effects that are frequently overlooked in public health discussions. Addressing these side effects is essential to ensure comprehensive care for individuals undergoing MAT. Increased awareness and discussion of these potential issues can improve support and outcomes for individuals in recovery.
In this article, we’ll examine some of the less-discussed drawbacks of common MAT medications.
Suboxone and Dental Issues
Suboxone, a combination of buprenorphine and naloxone, is a widely used MAT medication. According to Bicycle Health, Suboxone is around 1.8 times more efficient than non-medicated addiction rehabilitation options for keeping patients in treatment.
It has been demonstrated to lower positive drug tests by more than 14% in persons undergoing treatment. This emphasizes its critical significance in assisting recovery efforts.
One under-discussed side effect of Suboxone is its potential impact on dental health.
Suboxone can cause dry mouth, which can decrease saliva production and lead to cavities, gum disease, and even tooth decay.
People taking Suboxone should be especially vigilant about brushing and flossing regularly and seeing a dentist for regular checkups. To minimize the effects of dry mouth, sugar-free lozenges or gum can also be helpful.
The Legal Landscape Associated with Suboxone
Recently, there has been increasing concern about the connection between Suboxone and dental issues. TorHoerman Law notes that multiple lawsuits have been initiated against Suboxone’s manufacturers, claiming they did not adequately inform patients about the possible risks.
The Suboxone lawsuit centers on the argument that the medicine’s sublingual film form can be acidic and may contribute to tooth decay. In June 2022, the FDA updated the Suboxone warning label to include information about the potential for dental issues. The legal landscape surrounding Suboxone and dental complications is still evolving, with several lawsuits currently pending.
As noted in a July 2024 update from Drugwatch, about 677 lawsuits are pending in the Suboxone litigation. These lawsuits have been consolidated in an MDL in the Northern District of Ohio. There haven’t been any official settlements in these cases as of now.
Methadone and Heart Issues
Methadone, a commonly used MAT medicine, substantially lowers opioid cravings and symptoms of withdrawal. However, it has the potential to extend the QT interval, which is the duration for the heart’s lower chambers to contract.
A prolonged QT interval increases the risk of arrhythmias or irregular heartbeats. According to Healthline, the condition is also known as atrial fibrillation. Almost 130,000 people lose their lives to arrhythmia every year.
Regular EKG monitoring is essential for people on methadone to ensure their heart health. They should also avoid any drugs or substances that may extend the QT interval.
Naltrexone and Gastrointestinal Issues
Naltrexone works differently from other MAT medications. It blocks opioid receptors, preventing opioids from producing their euphoric effects.
Constipation is a common side effect of naltrexone. Staying well-hydrated, increasing fiber intake, and using over-the-counter laxatives can be helpful in managing it. If constipation is severe, a healthcare professional can recommend additional medications or treatment options.
FAQs
What is the new dental warning for buprenorphine?
The new dental warning for buprenorphine highlights its potential to cause severe dental problems, including cavities and tooth decay. This can occur in individuals using the medication for opioid addiction treatment. It is advised to maintain appropriate oral hygiene and schedule routine dental examinations to reduce these risks.
Does methadone drop heart rate?
Methadone can potentially lower heart rate, especially in high doses or when combined with other medications that affect heart rhythm. This is due to its impact on the QT interval, which can lead to bradycardia. Management by healthcare practitioners is required to control this risk.
Does naltrexone cause digestive issues?
Naltrexone can cause digestive problems like vomiting, nausea, and stomachaches. These side effects are typically more frequent at the start of treatment and usually lessen with time. Patients who have persistent or severe symptoms should notify their healthcare physician.
One essential weapon in the fight against opioid addiction is medication-assisted treatment or MAT. While medications like Suboxone and methadone are highly effective, they can cause under-discussed side effects. Suboxone can lead to dental problems due to dry mouth, highlighting the importance of good oral hygiene for those undergoing treatment.
Methadone can impact heart health, so regular monitoring is necessary. Naltrexone, while working differently, can cause constipation, manageable through diet and medication. We can ensure patients receive comprehensive care and experience better outcomes on the road to recovery by openly discussing these potential drawbacks.
